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Dear Wei,

you could use coot "Calculate->Model/Fit/Refine->Simple Mutate" also for
nucleic acids.
It may be worth running geometry idealisation in coot or refmac5 before
using the model in MR.

Tim

On 11/19/2011 09:44 PM, Wei Shi wrote:
> Hi all,
> I want to change a piece of DNA in pdb file to match the target DNA
> sequence in order to be used as a search model in molecular replacement.
> Does anyone happen to know how I could do this? Thank you so much!
> 
> Best,
> Wei
> 

- -- 
- --
Dr Tim Gruene
Institut fuer anorganische Chemie
Tammannstr. 4
D-37077 Goettingen

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