-----BEGIN PGP SIGNED MESSAGE----- Hash: SHA1 Dear Wei,
you could use coot "Calculate->Model/Fit/Refine->Simple Mutate" also for nucleic acids. It may be worth running geometry idealisation in coot or refmac5 before using the model in MR. Tim On 11/19/2011 09:44 PM, Wei Shi wrote: > Hi all, > I want to change a piece of DNA in pdb file to match the target DNA > sequence in order to be used as a search model in molecular replacement. > Does anyone happen to know how I could do this? Thank you so much! > > Best, > Wei > - -- - -- Dr Tim Gruene Institut fuer anorganische Chemie Tammannstr. 4 D-37077 Goettingen GPG Key ID = A46BEE1A -----BEGIN PGP SIGNATURE----- Version: GnuPG v1.4.10 (GNU/Linux) Comment: Using GnuPG with Mozilla - http://enigmail.mozdev.org/ iD8DBQFOyjTzUxlJ7aRr7hoRApYSAJ4xf8R1kjy+sl16WlQRGuOZuW4kbQCbBwB7 hY5x91qUynn4xFxrYHsN/kY= =HaRr -----END PGP SIGNATURE-----