I agree with Rafael, >From those pictures it looks like a sugar chain - maybe 2-3 saccharides in a row.
HTH D ============================ David C. Briggs PhD Father, Structural Biologist and Sceptic ============================ University of Manchester E-mail: david.c.bri...@manchester.ac.uk ============================ http://manchester.academia.edu/DavidBriggs (v.sensible) http://xtaldave.wordpress.com/ (sensible) http://xtaldave.posterous.com/ (less sensible) Twitter: @xtaldave Skype: DocDCB ============================ On 27 October 2011 17:27, Jacob Keller <j-kell...@fsm.northwestern.edu> wrote: > Dear Crystallographers, > > In the course of a reasonably smooth refinement, all of a sudden there > is a huge worm-hole-type blob in the electron density (see pics). Has > anyone seen this before? Is it some effect of the refinement > over-fitting or something? For some background, resolution is 2.2Ang > and there are 4mol/ASU, but one of them is markedly worse in terms of > density than the rest, and appears to be in a non-crucial part of the > lattice, as if just sitting in one of the interstices. R/Rfree is > ~19.5/24.5. > > Jacob > > -- > ******************************************* > Jacob Pearson Keller > Northwestern University > Medical Scientist Training Program > email: j-kell...@northwestern.edu > ******************************************* >
