Karolinska Institutet has a vacancy for A doctoral student with doctoral grant 
in Structural Immunology/Bacteriology 
Department
Department of Medicine, Huddinge 
Description of research group and project
Center for Infectious Medicine (CIM), Department of Medicine, Huddinge is 
looking for a PhD student who will work with Associate Professor Adnane Achour 
and his colleagues in order to determine the three-dimensional structures of 
virulence-associated proteins derived from various pathogens. The Achour 
research group is a part of the Center for Infectious Medicine (CIM), 
Department of Medicine Huddinge, and is localized within the Department of 
Microbiology, Tumor and Cell biology (MTC) at Solna campus. The research 
projects of the Achour group are bridging immunology and structural biology. 
The PhD student candidate will actively participate in projects aiming to 
unravel the molecular basis of action of specific pathogen-associated proteins. 
Besides X-ray crystallography, techniques and approaches included within the 
proposed projects include molecular biology, biochemistry and biophysical 
approaches such as surface plasmon resonance. The overall aim of the projects 
is to assess the molecular basis for recognition of ligands by specific 
pathogen-associated proteins and their mode of action. 
Duties and responsibilities
The proposed projects represent a unique opportunity for a PhD student to 
acquire deep insights into immunology/microbiology, biochemistry and structural 
biology using a variety of techniques already well established within the 
Achour laboratory. The duties and responsibilities of the PhD candidate are to 
lead the proposed project(s) under the close supervision of his/her 
supervisors, and in close collaboration with his/her colleagues within the 
research group. By the end of the PhD study period, the candidate should have 
acquired a deep knowledge in molecular biology and biochemistry as well as a 
broad knowledge in immunology and structural biology. The PhD candidate should 
demonstrate excellent ability to design, perform, interpret, critically assess 
and contextualize generated data from experimental work. Furthermore, he/she 
should demonstrate aptitude to discuss and spread research results to both the 
national and international scientific community as well as to the 
non-scientific community. 
Eligibility/Qualifications
The eligible candidate must hold a Master´s degree in immunology, biophysics, 
mathematics, biomedicine, bacteriology, cell biology or equivalent. Previous 
experience in molecular biology and/or biochemistry is desirable but not 
absolutely required. We are seeking a highly motivated, creative person with 
good technical skills. The successful applicant should be fluent in English, 
with excellent communication capacity combined with the ability to interact 
effectively and work productively in a team. Emphasis will be placed on 
personal suitability as well as genuine enthusiasm for the topic.

To be eligible, an applicant must 
1. hold a Master’s (second-cycle) degree 
2. have completed course requirements of at least 240 HECs, of which at least 
60 at second-cycle level, or 
3. have otherwise acquired essentially equivalent competence in Sweden or 
abroad. 

Those who meet the requirements for general eligibility before July 1st, 2007, 
i.e. had completed a programme of higher education for at least 180 HEC or the 
equivalent, will continue to do so until the end of July, 2015. 

Selection of qualified applicants is made on the grounds of their ability to 
benefit from doctoral (third-cycle) education. Karolinska Institutet applies 
the following assessment criteria: 
- Documented subject knowledge of significance to the research project
- Analytical skills confirmed by a scientific dissertation or the equivalent
- Other documented knowledge/experience of potential significance to doctoral 
(third-cycle) education in the subject 
An overall assessment of the applicants’ qualifications will be made. 

The vacancy will be filled on condition that the successful applicant is 
admitted to doctoral (third-cycle) education.

For further information on doctoral (third-cycle) education at Karolinska 
Institutet, see www.ki.se/doctoral.

Contact person: Ass. Prof. Adnane Achour, phone: 08-5248 6216, 076-8090567, 
adnane.ach...@ki.se 

Union representatives: SACO: Ingrid Dahlman, ingrid.dahlman@ki., OFR: Eva 
Sjölin, eva.sjo...@ki.se 
Form of employment:
Doctoral student 
Notes
A doctoral student with doctoral grant yrs 1, and 2.
Temporary doctoral student yrs 3, and 4.        
Please send your application, marked with reference number 6187/2011, to reach 
us by no later than November 6 2011       to KI jobb or, 
to Anna Maria Bernstein, M 54; Karolinska Institutet, 141 86 Stockholm, 
anna.maria.bernst...@ki.se. The following documents should be enclosed with 
your application in English or Swedish:
- Personal letter of introduction and CV
- Copy of degree certificate and grades             

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