Hi Kavya The resolutions of the structures mentioned in the paper were only examples, the Rfree/-LLfree minimisation method (which are actually due to Axel Brunger & Gerard Bricogne respectively) does not depend on resolution.
If the structures are already solved & refined, you don't need to do any model building, it should be within the radius of convergence with the new weights - it's only a small adjustment after all. Cheers -- Ian On Fri, Oct 14, 2011 at 6:12 AM, <ka...@ssl.serc.iisc.ernet.in> wrote: > Dear users, > > Can the optimization of the X-ray weighing factor > and B-factor (overall wt) as mentioned in the paper > Acta Cryst. (2007). D63, 1274–1281 by Dr.Ian Tickel, > be used for the refinement of the data sets beyond > the resolution range mentioned in the paper: 1.33 - > 2.55 Ang? > > Also the structures that were used to optimize these > parameters were already solved and refined, so when > we are solving a new structure to what extent does the > model has to be built before starting the optimization? > > Thanking you > With Regards > M. Kavyashree > > > -- > This message has been scanned for viruses and > dangerous content by MailScanner, and is > believed to be clean. >
