As a personal touch, I also find Biorad software much more intuitive.

This discussion, of course, is similar to comparing car brands -
experiences differ.

What mystifies me is a need for a service maintenance contract at all. Has hardware become so much less reliable than in the past?

Granted, this Akta line is confusing but my impression that it is three completely different machines, based on peristaltic pump, FPLC glass pumps and conventional HPLC pumps. In about 20 years next to a working old-style FPLC and two HPLC setups (Waters and Gilson), I haven't seen a single service call. Just about the only maintenance FPLC requires is changing pump seals, changing lamp in UV monitor and maybe changing valve distribution plate (all trivial even for a hardware-challenged person like me). In all these years I saw one thing wrong with HPLC - pump head ceased (related to a negligent care) and needed to be replaced completely. Well, and UV lamp replacements. That's it.

So, what are these magic Akta components that need constant care and repairs?

BTW, agree on Bio-Rad's software. Always felt that it is much more intuitive than Pharmacia's equivalents.

- Dima

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