On Tuesday, October 11, 2011 11:21:41 am Francis E Reyes wrote: > http://hoowstuffworks.blogspot.com/2011/10/adobe-demos-amazing-unblur-feature.html > > Though I can't really see the image myself... the gasp of the audience is > telling > > > With respect to existing density modification programs, I wonder if such > technology > (whatever it is) can ever clear up my messy density maps.
The technology is directly parallel to TLSMD analysis. It creates a model that includes a prediction of the blurring in the original image, or in our case the blurring in the map generated by Fourier transform of the original data. The difference is that in the case of a photograph one is interested in the altered image rather than the underlying model. In the case of a crystal structure one is interested in the underlying model rather than the electron density map per se. I have for a long time used the "motion-blurred photograph" parallel to explain how TLSMD works. See for example page 3 of http://www.ccp4.ac.uk/schools/APS-2009/tutorials/tls/Merritt30th.pdf Ethan -- Ethan A Merritt Biomolecular Structure Center, K-428 Health Sciences Bldg University of Washington, Seattle 98195-7742
