On Thu, 2011-09-15 at 15:10 -0500, Jacob Keller wrote: > Maybe one should do a gradient of > gluteraldehyde concentrations, then plot the deviation of the observed > cross-linked oligomerization from a theoretical null hypothesis?
Right - just do it side-by-side with a protein known to be monomeric of roughly the same size/lysine content... And what is the "critical concentration" of gutaraldehyde at which the false positives appear in your experience? -- "I'd jump in myself, if I weren't so good at whistling." Julian, King of Lemurs