Dear Jacob, Globalphasing has a new programm called Pipedream that should do just what you want. I am not sure if it is available to non consortium members.
Best regards, Alexander -----Original Message----- From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Jacob Keller Sent: Friday, August 26, 2011 10:43 PM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] HTP ligand screening Dear Crystallographers, I have ~30 data sets from ligand soaks of my protein of known structure (all approximately the same cell. Can anyone suggest a high throughput method which would do molecular replacement, refine, then output new blobs, perhaps as a water pdb file? I am sure they do this or better in pharma every day... Jacob Keller ******************************************* Jacob Pearson Keller Northwestern University Medical Scientist Training Program cel: 773.608.9185 email: j-kell...@northwestern.edu *******************************************
