On 8 Jul 2011, at 19:13, Katherine Sippel wrote: > I know that the PDB updated its validation server in May as described in > their news link but it seemed to indicate an increase in output options > rather than a change in criteria. Is anyone aware of what changes were made > to the validation server in regards to the preferred geometrical and > stereochemical features?
As far as I can tell empirically, if I run the validation server today it complains about a) waters which make a perfectly good contact with a residue in a different ASU b) waters which make a perfectly good contact with metal ions or with other waters which themselves make a perfectly good contact with the protein. and this means it's really not much use for validation of large complicated proteins with hundreds of waters. Tom
