Postdoc opening at the MRC Laboratory of Molecular Biology, Cambridge, UK.

Murray Stewart's Structural Cell Biology group at the MRC Laboratory of Molecular Biology in Cambridge is seeking a postdoctoral scientist (3-year Career Development Fellow position) to work on the structural basis of the nuclear export of mRNA.

The successful applicant will use a combination of structural, biochemical and molecular approaches to establish the molecular mechanism of mRNA nuclear export and to determine the molecular basis for the formation and disassembly of export-competent mRNP particles. Applicants should have a PhD, together with practical experience in X-ray crystallography, Molecular Biology and Biochemistry, especially with respect to determining the structure of proteins, growing crystals, determining binding constants, expressing proteins in bacteria, and site-directed engineering of mutants. Experience in nuclear transport or yeast Cell Biology and having a strong publication record, with at least one first-author paper in a peer-reviewed journal, would also be advantageous.Further information can be obtained from Dr Stewart (m...@mrc-lmb.cam.ac.uk <mailto:m...@mrc-lmb.cam.ac.uk>) or from http://www.jobs.ac.uk/job/ACT935/career-development-fellow/

The successful applicant will be awarded an MRC Career Development Fellowship, which is a three year training and development position for a postdoctoral scientist who has recently completed their doctoral studies or is moving into a new research discipline.A starting salary of £26,022 to £28,178 per annum will be supported by a flexible pay and reward policy, 30 days annual leave entitlement, an optional MRC final salary pension scheme and excellent on-site sports and social facilities.

Applications are handled by the RCUK Shared Services Centre; to apply please visit the job board at https://ext.ssc.rcuk.ac.uk <https://ext.ssc.rcuk.ac.uk/> and complete an online application form. Applicants who would like to receive this advert in an alternative format (e.g. large print, Braille, audio or hard copy), or who are unable to apply online should contact RCUK by telephone on 01793 867003, Please quote reference number IRC23438.

Closing date: 27 June 2011Interview date 4 July 2011.

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