Dear all, I have a protein molecule with two flexible domains. For a 2.8 angstrom data, I could get MR solution for the larger domain but not for the smaller domain (around 80 aminoacids). The second domain appears as extra density showing its presence , but does not allow manual model building on it, since it appers to be smeared. I would like to run a phaser with some 30000 structures that I have for this protein from a simulation. Would it be possible to do this in my computer? If so, how can I do this? Any suggestions on this will be appreciated. Thanks in advance.
regards, Wandu