> related to what I feel is recent revival of the significance of the R-values
....because it's so handy to have one single number to judge a highly complex nonlinear multivariate barely determined regularized problem! Just as easy as running a gel! Best BR -----Original Message----- From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Ed Pozharski Sent: Thursday, March 03, 2011 8:19 AM To: CCP4BB@JISCMAIL.AC.UK Subject: Re: [ccp4bb] I/sigmaI of >3.0 rule On Thu, 2011-03-03 at 08:08 -0700, Bart Hazes wrote: > I don't know what has caused this wave of high I/Sigma threshold use > but here are some ideas > It may also be related to what I feel is recent revival of the significance of the R-values in general. Lower resolution cutoffs in this context improve the R-values, which is (incorrectly) perceived as model improvement. -- "I'd jump in myself, if I weren't so good at whistling." Julian, King of Lemurs