Dear group members, I would also like to bring this second opening to your attention:
ANNOUNCEMENT TITLE: 2 years Post-doctoral position in structural immunology with applications in T cell and NK cell receptor recognition of MHC class I and class II complexes in Stockholm, Sweden DEADLINE FOR APPLICATIONS: 25 Mars 2011 TYPE OF POSITION: Post-doc AFFILIATION INSTITUTION/DEPARTMENT: Center for Infectious Medicine (CIM), Department of Medicine, F59 Karolinska University Hospital in Huddinge, Karolinska Institutet, 16933 Stockholm. LOCALIZATION OF THE ACHOUR LABORATORY: Department of Microbiology, Tumor and Cell Biology (MTC), Nobelsvägen 13, Karolinska Institute, 171 77 Stockholm. CONTACT PERSON: Adnane Achour, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, S-171 77 Stockholm, Sweden. e-mail address: adnane.ach...@ki.se, Phone: +46-8-5248 6216, Fax: +46-8-30 42 76, website: http://www.medhs.ki.se/cim/ DESCRIPTION/REQUIREMENTS: A post-doctoral position is available for an enthusiastic individual for a period of at least two years within the laboratory of Assoc. Prof. Adnane Achour at the Center for Infectious Medicine (CIM), Karolinska Institutet in Stockholm, Sweden. The candidate should be a good team-player, with excellent knowledge of X-ray crystallography and biochemistry. Insights in TCR/MHC interactions are an advantage. but not absolutely necessary She/he will help to co-supervise PhD students and will collaborate with other post-doctoral fellows in the group. She/he will be responsible for the expression, purification, crystallization and structural analysis of proteins that are involved in the structure of the T cell and NK cell synapse. The prime targets of this project are T and NK cell receptors and a large array of MHC class I and class II alleles as well as other co-receptors. Site directed mutagenesis studies will be combined with a wide array of biochemical and immunological assays, as well as imaging, in order to assess the molecular mechanisms underlying the modulation of T cell activation in cancer and infection-related projects. Determination of crystallization conditions as well as the determination and interpretation of three-dimensional structures of several of these proteins, alone and in complex, should be undertaken by the candidate in close collaboration with other members of the research group. The Achour structural biology research group at CIM is well equipped for all aspects of modern structural biology, with state-of-the-art laboratories for molecular biology, recombinant expression in bacterial and eukaryotic systems, biochemistry, biophysics and X-ray crystallography. Excellent synchrotron access is available at BESSY and ESRF. Applicants must have a PhD, and experience in recombinant expression, protein purification, crystallization and X-ray crystallography. Information on our previous work in this field can be found by searching PubMed and via the CIM website APPLICATION PROCEDURE: The application should include a personal motivation letter, a CV (including in particular any experience relevant to the position announced) as well as the names and contact details of 2 references. The applicants should also submit a list of publications and submitted manuscripts. Adnane Achour, Associate Professor fax:+46-8-30 42 76 phone:+46-8-5248 6216 Center for Infectious Medicine; Department of Medicine, Karolinska University Hospital Huddinge Karolinska Institute 141 86 Stockholm, Sweden url: http://ki.se/cim url:http://www.medhs.ki.se/cim/medhs_eng.asp?Id=12&tabell=medhs_english
