Dear all,

Can you please post the message below to the CCP4bb.

Thank you very much in advance 

Best wishes

Frank





The Beatson Institute for Cancer Research
Postdoctoral Scientist – Protein Crystallography
Salary from £25,500 – £38,000 (Depending on experience)

3 year fixed term contract.

The Beatson Institute in Glasgow is one of Europe's leading cancer research 
centres. It is core funded by Cancer Research UK and supports cutting edge 
research on the molecular mechanisms of cancer development. The Institute 
provides an outstanding research environment, underpinned by state-of-the art 
core services and advanced technologies. 

We are seeking an experienced protein crystallographer to investigate the 
structures of cancer-related proteins. Our group is particularly interested in 
members of the kinesin superfamily with a focus on human mitotic kinesins and 
their associated proteins. Several of these proteins are good targets for drug 
development in cancer chemotherapy. In addition, we strongly collaborate with 
other groups at the Institute to determine structures of different types of 
proteins involved in cancer development.

We have a well-equipped laboratory for all aspects of structural work including 
ÄKTA protein purification systems, a Mosquito nano-drop robot, automated 
storage and visualisation systems (Formulatrix at 4°C and 19°C), and a Rigaku 
HighFlux Homelab microfocus diffraction system. In addition, we are well 
equipped to characterise the biochemistry of protein - inhibitor complexes 
towards the optimisation of lead compounds in collaboration with our chemistry 
colleagues. For more details please refer to our web site at 
http://www.beatson.gla.ac.uk/Regulation-of-Cancer-Cell-Proliferation-and-Growth/Frank-Kozielski-Molecular-Motors.html

The successful applicant must hold a PhD in protein crystallography and have 
successfully completed at least one post-doctoral position in the same field. A 
good theoretical background in protein crystallography and extensive experience 
in the determination of protein structures will be strongly favoured. 
Experience with eukaryotic expression systems would be an advantage.

Applications with CV and names of two referees should be sent to Prof. Frank 
Kozielski, The Beatson Institute for Cancer Research, Garscube Estate, 
Switchback Road, Bearsden, Glasgow, G61 1BD, Scotland (FAX: +44 141 942 3653) 
or by Email to f.koziel...@beatson.gla.ac.uk.

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