Hi All
I'm curious the effect of small impurities in commercially synthesized
compounds on ITC and its analysis. Say if compound Y is the high
affinity binder, but you make a derivative that differs from a single
functional group from Y (you used Y to make this new compound) and you
never are able to completely get rid of Y. How does this affect the
analysis of determining the derivative's affinity by ITC?
References or personal experience is appreciated!
F
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Francis E. Reyes M.Sc.
215 UCB
University of Colorado at Boulder
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