Fully funded postdoctoral positions at Yale University School of Medicine are available immediately from highly motivated, enthusiastic individuals with a strong interest in the structure, function, and pharmacology of signaling proteins implicated in neurological and neuropsychiatric diseases. We are presently focusing our efforts on central nervous system transporters using a combination of steady-state kinetics, radioligand binding, and X-ray crystallography.
The laboratory is located in newly-renovated space in the Department of Cellular and Molecular Physiology in a highly collaborative environment. We have regular access to a Mosquito crystallization robot, in-house X-ray generator w/ R-axis IV++ detectors, LINUX workstations, and synchrotron beamlines. The lab's proximity to the renowned W.M. Keck facility will additionally enable the successful candidate to conduct detailed experiments in static and dynamic light scattering, isothermal titration calorimetry, steady-state and stopped-flow fluorometry, and surface plasmon resonance. Candidates must hold (or soon expect to hold) a Ph.D. in biochemistry, biophysics, or a related field. A strong background in recombinant DNA methods, protein expression and purification, and X-ray crystallography is required. Prior work with membrane proteins, tissue culture, and functional assays is preferred but not necessary. The ideal candidate will also possess excellent oral and written English communication skills and work well in a collaborative environment. For more information, please contact satinder.k.si...@yale.edu You may also be interested in reading the following review article: Singh, S.K. (2008) LeuT: a prokaryotic stepping stone on the way to a eukaryotic neurotransmitter transporter structure. Channels 2, 380-389 Applicants should send a CV along with a one-page summary of previous research experience and interests and arrange to have 3 reference letters sent to satinder.k.si...@yale.edu ----------------------------------------------------- Satinder K. Singh, Ph.D. Assistant Professor Dept. Cellular & Molecular Physiology Yale University School of Medicine 333 Cedar Street, SHM B147 Lab room #: SHM BE11/BE17 P.O. Box 208026 New Haven, CT 06520-8026 Office: 203-737-6477 Lab: 203-737-4861 Fax: 203-785-4951 Cell: 612-961-4948 E-mail: satinder.k.si...@yale.edu -----------------------------------------------------
