Holes in the diffraction pattern, to make it simple, means holes in the electron density maps. So the resulting electron density maps will be more noisy than electron density maps computed with complete data sets. It is possible to replace the missing amplitudes by non-random estimates during density modification (solvent "flattening" or NCS averaging).
Fred. > Message du 10/05/10 15:48 > De : "Rex Palmer" > A : CCP4BB@JISCMAIL.AC.UK > Copie à : > Objet : [ccp4bb] Incomplete data > > If you measure a set of diffraction data without any particular restraints > and it turns out, say at a given theta max, to be only 80% complete, what does this imply? > > Rex Palmer > Birkbeck College
