hi all
this is just a basic query or rather for discussion.
1. What maintains the active state of the protein during
crystallization under different condition which is altogether
different condition from what that protein might be in vivo?
2. what is the probability of a nonfunctinal state of a protein
getting crystallize?
3. Is crystal structure the actual structure of the macromolecule or
is it rather near-actual structure?
i apologize if just in case this question is not upto level of discussion.
thanks
--
Sudhir Kumar
Research Scholar
Structural Biology Laboratory
SLS, JNU,
New Delhi-110067
