Please bring this position to the attention of anyone in your lab who might be interested.
Thanks, Kendall The Scripps Research Institute Palm Beach Co, Florida Post-doctoral Position: Nuclear Receptor Signaling and Structure-Based Drug Design The Scripps Research Institute has established a major science center in Palm Beach County, Florida, focusing on biomedical research, technology development and drug design. A post-doctoral fellowship position is available to study nuclear receptor signaling and structure based drug design in the laboratory of Associate Professor Kendall Nettles. Candidates should have a PhD degree and experience in protein crystallography and/or a good background in molecular biology and protein biochemistry. The laboratory is equipped with robots for high throughput cloning, protein purification, solution mixing and crystallization, and automated crystal visualization. The institute has a home source, and dedicated time at SSRL and APS. We use a variety of structural and molecular approaches to understand the connections between small molecule ligand, receptor structure and function, and endocrine physiology. Ongoing projects include investigation of the structural basis for tissue and pathway specific signaling through the estrogen and glucocorticoid receptors, signal transduction across the RXR heterodimer interface, and structure-based drug design. The fellow will interact closely with the Drug Discovery, Advanced Technology, and Genomics groups at Scripps Florida to take advantage of other automated technologies, including robots for small molecule screening and transfection. Please send curriculum vitae, a brief statement describing research experience and scientific interests and the names of at least two references to: Kendall W. Nettles, PhD Associate Professor, Department of Cancer Biology The Scripps Research Institute 130 Scripps Way Jupiter Fl 33458 Email: knett...@scripps.edu
