Dear all,
the beamline scientist position for the long-wavelength macromolecular
crystallography beamline I23 at Diamond Light Source has been opened.
Diamond Light Source is a new synchrotron and a leading scientific facility of
its type in the world. Located on the Harwell Science and Innovation Campus in
South Oxfordshire, UK, we host facilities supporting cutting edge research in
all fields of science.
The long wavelength macromolecular crystallography beamline I23 will be a
dedicated beamline for experimental phasing experiments utilizing multiple or
single wavelength anomalous diffraction techniques. Uniquely, it will be
optimized for operation in the wavelength range from 1.5 to 4 Å. To overcome
the detrimental effects of increased absorption and larger diffraction angles
both the end station and the detector will be optimized for this wavelength
range. An X-ray tomography set up will be directly integrated into the design
to determine the size and volume of the crystal, solvent and support to allow
an analytical absorption correction of the diffraction data. It is currently in
the design phase to go into user operation in 2013.
The successful candidate should have a Ph.D. in biology, biochemistry,
chemistry, physics, or related fields, preferably with some synchrotron
research experience and is expected to initiate a competitive programme of
research in an area relevant to the beamline activities (Macromolecular
crystallography or related areas of research). In addition the beamline
scientist will assist the principal beamline scientist with the design,
installation, commissioning and maintenance of the beamline. Moreover, it is
highly desirable that the successful candidate can contribute to at least one
of the major areas of focus of the beamline project which can be broadly
summarized as:
*
Development of innovative sample handling and mounting techniques.
*
Implementation of analytical absorption correction utilizing X-ray
tomography.
*
Optimization of data analysis software for cylindrical detector
geometry.
The Rutherford Appleton site with its world leading facilities, including
Diamond, ISIS and CLF offers a highly multidisciplinary environment. Together
with the suite of five existing MX beamlines and the Membrane Protein
Laboratory (MPL) embedded in Diamond, the adjacent Research Complex at Harwell
due to open in early 2010 will house a range of life and physical science
activities, including both CCP4 and OPPF-UK, the national facility for protein
production and crystallization providing exceptional opportunities for
synergies and collaborations. If you enjoy working as part of a highly
motivated team, this position will offer you a great opportunity to contribute
to this unique project and to undertake research at a world-class facility.
For further information please see the following webpage
(www.diamond.ac.uk/Home/Jobs/Current/DIA0543.html
<http://www.diamond.ac.uk/Home/Jobs/Current/DIA0543.html> ) and for an informal
discussion contact me on 01235 778560 or armin.wag...@diamond.ac.uk
<mailto:armin.wag...@diamond.ac.uk>
Please note that this is a open vacancy, a first round of interviews is planned
during the second half of February.
All the best,
Armin
Dr. Armin Wagner
Principal Beamline Scientist
Long-Wavelength Macromolecular Crystallography
Diamond Light Source
Diamond House DH2-52
Chilton, Didcot
OX11 0DE
United Kingdom
Tel.: 0044 (0)1235 778560
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