Dear All, Happy New Year
I am working with a 2.06 Ang resolution structure in F432 space group and further using REFMAC (also tried Phenix) program for refinement of my model. Every thing in the structure seems good, R factor/ R free= 18.59/20.77 but the structure is too noisy (blobs of difference Fourier with red as well as green density). As such electron density is looking good for the protein part. Is there any parameter which i had to check. Thanking you in advance Rajan -- ************************************************ Current Address: Rajan Vyas Research Scholar Deptt. of Biotechnology Panjab University Chandigarh, India 160014 Mob. +919417374197 Fax: +91-172-2625254 ************************************************