Hi Matthias,
S-SAD seems to require really strong diffraction, high symmetry, and
high data redundancy. In the end, the S ano signal is pretty weak even
at longer wavelength. While S-SAD might work, Iodide soaks might be a
much more practical approach. Iodide has some 6 electrons at CuKa.
... has given us 2 structures for SSGCID during the past month...
Cheers
Jan
On Nov 11, 2009, at 4:16 AM, Matthias Zebisch wrote:
Dear bb!
What is the optimal wavelength for Sulfur SAD phasing?
Is it 1.9A or should one go below that to reduce absorption/damage.
Also, would the same wavelength be appropriate to maximize anomalous
scattering to position chlorides, calcium, sulfate in already phased
structures?
Thanks in advance,
Matthias
--
Jan Abendroth
deCODE biostructures
Seattle / Bainbridge Island WA, USA
work: JAbendroth_at_decode.is
home: Jan.Abendroth_at_gmail.com
