Postdoctoral and Ph.D. positions are available at Laval University Hospital Research Center (CHUQ), for the study of structural biology, cell biology and function of important enzymes. Our research involves new projects in steroid enzyme structure-function and in estrogen synthesis pathways, supported by the Canadian Institutes of Health Research (CIHR). Inhibitors of steroid enzymes will be searched for the treatment of breast cancer and will be tested in cells and animal models. Crystallography, cell biology and enzymology back grounds are highly welcome.
Since the determination of the first human steroid enzyme structure, the type 1 17beta-hydroxysteroid dehydrogenase, we have determined a series of enzyme structures, resulting in leads for the cancer therapy. Expertise in crystallizing membrane and hydrophobic proteins, cell biology and enzymology are available in the laboratory with state-of-the-art facilities. Quebec City, with its original European style, is alongside the St. Laurence river, providing a beautiful and an excellent research environment. All positions will be well remunerated at CIHR levels, while the living expenses are modest in Québec City. For those who are interested in the above projects, please send your C.V. to sx...@crchul.ulaval.ca
