Yes

Dale Tronrud

Mike England wrote:
Hi all,

I will appreciate your comments on the following case:

I have two datasets from the same or identical crystals. Initially, I
refine a structure against the first data set  and later on switch to
another dataset  for further refinements.
Do you think, my Rfree will be biased as Rfree reflections in second
dataset may be in fact Rwork reflections in previous datasets ?

Thanks in advance,

Mike

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