At the Institute of Biochemistry of the University of Lübeck (Germany), job openings for

*doctoral candidates and postal doctoral candidates in structural virology
*
are available to reinforce the ongoing research projects:

1. Postal-doctoral candidate in crystallography / structural virology (initially for 2 years, possibly up to 6 years ("habilitation" option). Salary scale: E13 TVL. Job identity number: 535/09

2. Doctoral candidate for structural virology and drug design (initially for 2 years). The aim of this project, in cooperation with the Heinrich-Pette-Institute in Hamburg, is the inhibition of the nuclear export of HIV-RNA. Salary scale: E13 TVL in part-time: 50%. Job identity number: 536/09

3. Doctoral candidate for structural virology (limited to 3 years). Aim of this project, in cooperation with the Bernhard-Nocht-Institute of tropical medicine in Hamburg, is the elucidation of the structure of the Lassavirus L protein. Salary scale: E13 TVL in part-time: 50%. Job identity number: 537/09


*BMBF-funded Junior Research Group at DESY, Hamburg*

At the “laboratory for structural biology of infection and inflammation“, founded by universities of Lübeck and Hamburg and located at the DESY area, we plan to establish a BMBF-funded Junior Research Group for “structural infection biology under use of new radiation sources“. Aim is to explore new avenues for studying biomolecules and complexes relevant to infection by means of Raman spectroscopy with the UV free electron laser FLASH as well as SAXS and crystallography at the storage ring PETRA III.

4. Junior research group leader (initially for 2 years, up to 5 years possible ("habilitation" option). Salary scale: E14 TVL. The scientist is expected to participate in the teaching programme for medicine students at the University of Lübeck (Lehre in deutscher Sprache; die Lehrverpflichtung richtet sich nach § 4 der Lehrverpflichtungsverordnung Schleswig-Holstein). Job identity number: 538/09

5. Postal doctoral candidate (initially for 2 years). Salary scale: E13 TVL. Job identity number: 539/09

6. Technical assistant (initially for 2 years, up to five years possible). Duties cover sample preparation and technical assistance with the experimental work. Salary scale: up to E 8 TVL in part-time: 50%. Job identity number: 540/09

The Institute of Biochemistry investigates the molecular basis of intracellular infection by RNA viruses (primarily Coronaviruses incl. the SARS virus as well as Influenza virus and Enteroviruses), bacteria and protozoans, with the aim of the design and the development of new anti-infective compounds (see PLoS Pathogens 5, e1000428 (2009); Protein Science 18, 6 (2009); J. Mol. Biol. 383, 1081 (2008); Chem. Biol. 15, 597 (2008))). The work covers identification of potential virulence factors by means of proteomics, and by recombinant production, crystallisation and X-ray structural analysis of these proteins as well as the design and chemical synthesis of inhibitors. The Institute is well equipped and has direct access to synchrotron radiation at DESY. Please, consult our web page (www.biochem.uni-luebeck.de) for further information.

The university is eager to reach a balance between female and male employees and strives to employ disabled persons. Hence, disabled applicants and females are especially requested to apply.

The director of the Institute of Biochemistry, Prof. Dr. Rolf Hilgenfeld, can be contacted for further information. Tel. +49-451-5004060 or Email: hilgenf...@biochem.uni-luebeck.de

Applications (please quote the job identity number!) should be mailed by September 30, 2009, to:

University of Lübeck
Dezernat Personal
Ratzeburger Allee 160
D-23538 Lübeck
Germany.

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