This happened to me previously, and the only thing that worked for me was to
lower the protein concentration.  I was setting my protein up at 10 mg/mL,
only to find skins on nearly all the drops.  I would damage the crystals
trying to get them out of the drops... I lowered my protein concentration to
7.5 mg/mL... the crystals still grew, and the skin didn't.  

This seems to happen a lot when you set up crystals with PEGs, so you might
be able to lower the concentration of PEG as well.

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