Postdoctoral position available:
Applications are invited for a postdoctoral position to investigate
the structure and biochemistry of proteins involved in Gram-negative
bacterial cell wall recycling. Peptidoglycan metabolites produced
during cell wall turnover are found to regulate an increasing number
of bacterial processes, including the induction of antibiotic
resistance in a number bacterial species that cause opportunistic
infections in humans. We are focused on understanding the biology of
the cell wall recycling pathway, with the goal of developing small
molecule based strategies to disrupt the pathway and suppress
antibiotic resistance mechanisms that are coupled to it (J. Biol.
Chem. 2007; 282:21382-91, 2009 Antimicrob Agents Chemother. 2009
53:2274-82, Protein Sci. 2009;18:1541-51). A number of projects are
well advanced, some with crystals already in-hand. More project
information can be found at: http://umanitoba.ca/faculties/science/microbiology/staff/mark/
We seek enthusiastic applicants who hold a PhD in biochemistry or
related field. Candidates should have a strong background in molecular
biology, protein purification/crystallization and protein X-ray
crystallography.
Our group is located in the Department of Microbiology, University of
Manitoba, Winnipeg, Manitoba, Canada. The laboratory includes state-of-
the-art Rigaku instrumentation (Micromax 007 HF, X-stream cryosystem
and R-axis 4++ detector) and has access to the newly commissioned
Canadian Light Source Synchrotron, which is a short drive away.
The University of Manitoba (http://umanitoba.ca/) is the largest
University in the province (over 30,000 students, faculty, and staff)
and hosts a large, interactive biomedical research community.
Winnipeg is a vibrant, multicultural city with an outstanding
performing arts scene, numerous cultural events and festivals, and
great dining (http://www.destinationwinnipeg.ca/). With over 110,000
fresh water lakes in our province alone, there is also much to explore
for those who love the outdoors.
Salary will be in accordance with the Canadian Institutes of Health
Research (CIHR) (http://www.cihr.ca/ ) standards. Fellowship funding
is also available through agencies such as the CIHR and the Manitoba
Health Research Council (MHRC) (http://www.mhrc.mb.ca/).
The University of Manitoba encourages applications from qualified
women and men, including members of visible minorities, Aboriginal
peoples, and persons with disabilities. All qualified candidates are
encouraged to apply.
Please direct inquiries and CV's (including names of three referees)
to the following email address:
brian_m...@umanitoba.ca
=========================
Brian L. Mark, MSc, PhD
Assistant Professor
Department of Microbiology
Room 418, Buller Building
University of Manitoba
Winnipeg, Manitoba
CANADA R3T 2N2
Phone (204) 480-1430
Fax (204) 474-7603
Web: http://www.umanitoba.ca/science/microbiology/staff/mark/
