Current EU IPTG prices in euros, approximate, without tax, delivery or currency exchange fees. Prices are quoted as to my best knowledge, but of course may be different when you order at a different time or from a different place. I do not claim it is complete.

Apollo Scientific (UK): 5 g 18 euros, 25 g 85 euros
Biosynth (Switzerland): 10 g 40 euros, 25 g 89 euros, 50 g 160 euros, 100 g 286 euros ForMedium (UK): 1 g 9 euros, 5 g 28 euros, 10 g 51 euros, 25 g 118 euros, 100 g 378 euros, 250 g 765 euros Melford (UK): 1 g 10 euros, 5 g 31 euros, 10 g 56 euros, 25 g 131 euros, 50 g 244 euros, 100 g 450 euros
Nzytech (Portugal): 1 g 28 euros, 5 g 52 euros
Eurogentec (via Cultek): 1 g 21 euros, 5 g 84 euros
Qiagen (via Izasa): 5 g 142 euros
Promega: 50 g 1140 euros, 5 g 181 euros, 1 g 61 euros
Invitrogen: 1 g, 44 euros
Sigma-Aldrich: 5 g 250 euros, 10 g 494 euros

Fermentas was also mentioned at 33 pounds for 5 g, but their web does not let you see the price unless you register (it also does not mention Spain in the shipping list, perhaps it has a distributor here I am unaware of). It appears UK/Swiss companies are the cheapest, and the UK is in Europe, although some people seem to think otherwise. Seriously, for us ordering the UK is as easy as ordering from Spain or other European countries. I am not sure how easy ordering from Switzerland would be, I have never tried... All people give good refs of the supplier used (i.e. absence of expression problems), except for one person, who only uses Sigma IPTG after problems with other sources.

Another supplier mentioned without EU distributors was:
Gold BioTechnologies: 25 g 99 USD, 100 g 309 USD, 300g 799 USD

Several people mentioned Studiers auto-induction methods, which avoids having to use IPTG and gives them better cell density and, in some cases, more expression of soluble protein.

Thanks to all for their comments and knowledge of companies I had never heard of and did not find with Google,

Mark




Mark J. van Raaij
Dpto de Bioquímica, Facultad de Farmacia
Universidad de Santiago
15782 Santiago de Compostela
Spain
http://web.usc.es/~vanraaij/

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