[ccp4bb] pH sensitive fluorescent dye

[Daniel Jin]

Hi,



Sorry for the off-CCP4 question. Crystallographers are now doing everything...



We are looking for a fluorescent dye that will be turned on, or increase
signal, when pH goes from neutral to acidic. More specifically, we would like
to monitor the internalization of a protein into the acidic endosome. There are
dyes that will be quenched at low pH. But we want something that willl do the
opposite. Any information will be highly appreciated.

 

Best,

Daniel