Greetings All --

I am posting this on behalf of the HR department here at Exelixis.  Our 
Fermentation department provides all of our protein resources for 
high-throughput assay, cell biology and structural biology.  Our structural 
biology protein "consumption rates" are comparable to the larger structural 
genomics initiatives, so someone with that sort of background and experience 
would be an especially ideal candidate.

Please mention this to anyone you think is appropriate and might be interested 
in relocation to the San Francisco Bay Area of sunny* California!

Cheers,
Tom

*Full disclosure: yes, we have some fog too... But snow is generally properly 
kept to where it belongs: about a 3 hour drive into the Sierra Nevada 
mountains...   :)



Here are the details:

Assistant Research Scientist II

Job ID #: 667
Location: South San Francisco, CA
Position Type: Full-Time Regular
Department: Genome Biochemistry
Education Required: Bachelors Degree
Experience Required: 1 - 3 Years
Apply: Online at www.exelixis.com

We are seeking a professional to join our fermentation team in a hands-on 
laboratory role.  Duties include cell culture maintenance, scale-up and 
optimization of protein expression, and biomass production for multiple drug 
discovery projects. The successful candidate will assist in planning and 
development of new methodologies and laboratory protocols to improve the 
efficiency and productivity of the fermentation process.  You will prepare and 
organize data for presentation and project status reports at individual, group, 
and departmental research meetings.  You will be expected to maintain 
familiarity with current scientific literature relevant to the research 
experiments and programs.

BS/BA degree in Biology, Biochemistry, or Chemical Engineering and one year of 
related experience; or MS/MA degree in related discipline or combination of 
experience and education/training.  Familiarity with protein expression 
analysis tools such as Western blotting, SDS-PAGE, and activity analysis are 
desired, as would knowledge of expression construct design and protein 
purification techniques.  The qualified candidate should have experience in the 
production of recombinant proteins from systems such as E. coli and/or insect 
cells using fermentors and bioreactors from 5 to 80 L scale.  Must be able to 
lift at least 40 lbs.

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