Dear Richard,
the low resolution reflections are important for any data set, whether this is a high or medium resolution data set: they describe features corresponding to the size and global position of the crystallized molecule. That's why they are important for molecular replacement, for low resolution phasing, etc., but they have to be measured carefully with respect to overloads and noise or partial cut-off effects close to the beam stop.
Cheers, Bruno At 17:22 20/02/2009, Richard Gillilan wrote:
Several times I have heard that low order (small angle) reflections are more important when solving low-resolution structures. I presume it is more than just a question of obtaining greater number of reflections. Does anyone know why low-order reflections are so important in these cases? Richard Gillilan MacCHESS
############################################################################ Dr. Bruno P. Klaholz Department of Structural Biology and Genomics Institute of Genetics and of Molecular and Cellular Biology IGBMC - UMR 7104 - U 964 1, rue Laurent Fries BP 10142 67404 ILLKIRCH CEDEX FRANCE Tel. from abroad: 0033.388.65.57.55 Tel. inside France: 03.88.65.57.55 Fax from abroad: 0033.388.65.32.76 Fax inside France: 03.88.65.32.76 e-mail: klah...@igbmc.fr websites: http://www.igbmc.fr/ http://igbmc.fr/recherche/Dep_BSG/Eq_BKlah/index_uk.html
