There is an option to do harmonic restraints:
external harmonic chain [ch] residue [res] insertion [ins] atom [n]
[altcode [a]] [sigma [value]]
or
external harmonic residues from [residue_number] [chain_name] to
[residue_number] [chain_name] sigma [value] sigma 0.1
For example:
external harmonic chain A residue 225 atom CA will put harmominc
restraint on this atom external harmonic residues from 225 A to 250 A
sigma 0.02
Have a look for description for this and other newer keywords in:
http://www.ysbl.york.ac.uk/refmac/data/refmac_news.html
regards
Garib
On 27 Jan 2009, at 13:46, Andrii Ishchenko wrote:
Is there a possibility in refmac5 to fix atomic positions of some
part of
the molecule and to refine the other part? I couldn't find a proper
keyword
in keywords list:(
