Post-doctoral positions in macromolecular crystallography and NMR spectroscopy at the University of Pittsburgh in the Department of Structural Biology. There are several postdoctoral positions available immediately, with opportunities to work in projects related to Metabolic Membrane Proteins and to the Pittsburgh Center for HIV Protein Interactions (http://www2.structbio.pitt.edu/hivppi/site/index.php ). These positions are in the laboratory of Professors Angela M. Gronenborn (NMR/X-ray) and Joanne I. Yeh (Macromolecular X-ray crystallography).

The resources for X-ray Crystallography and NMR spectroscopy are outstanding. The X-ray Crystallography Facility includes automated crystallization screening and imaging, two high flux rotating anode generators, two CCD and two image plate detectors, and access to synchrotron time at SER-CAT; additional information can be found at (http://www2.structbio.pitt.edu/hivppi/site/cores_xray.php ). The NMR facility (http://www.structbio.pitt.edu/drupal-5/?q=nmr) comprises of a total of six spectrometers dedicated to biological NMR. These include three 600 MHz spectrometers, 700 MHz, 800 MHz and 900 MHz spectrometers. All spectrometers are fully equipped with hardware for all modern multinuclear experiments including triple-axis gradients and the capability for multi-channel pulsing with deuterium decoupling. Cryoprobes have been installed at every field strength.


Candidates should have a Ph.D. in structural biology or related fields (Chemistry, Physics, Biochemistry, Biophysics, Molecular Biology); experience in biological NMR or macromolecular crystal structure determination, including protein crystallization, data collection/ processing, structure determination and model refinement a plus. Please direct inquiries; or send your CV and the names and contact information for three references to Ms. Janet Zambotti (NMR) or Dr. Laurie Betts (X-ray crystallography) to the following e-mail address:


Laurie Betts
X-ray Crystallography Facility Manager
Department of Structural Biology
University of Pittsburgh
3501 Fifth Avenue 1047 BST3
Pittsburgh, PA 15260
412-383-5839
Email:  lab...@pitt.edu

Janet Zambotti
Assistant to Angela M. Gronenborn
Department of Structural Biology
University of Pittsburgh School of Medicine
3501 Fifth Avenue, 1047 BST3
Pittsburgh, PA  15260
Telephone – 412/648-9866
Email – zambo...@pitt.edu









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