Dear all, I am now refining one structure in space group C2 with 2 molecules, however we find the data can be processed in C2221 with 1 molecule. The questions are:
1. Can I still use space group C2 instead of C2221, even if the two molecules almost have crystallographic symmetry? Should I provide any excuses? 2. Is there any indication or necessity to refine structures in lower space group instead of higher? Many thanks!
