Just wanted to clarify the history of the foam Dewars for posterity:

- they were developed at the ALS when Gerry McDermott was head of the BCSB 
group here, and Jon Spear was a member of the group (Gerry was his supervisor 
at that time)

- after we had several glass Dewars implode, Gerry asked Jon specifically to 
try to make a Dewar out of a different material. Gerry might even have 
suggested trying the foam (they were originally made from the same material as 
is used in Yoga mats)

- Gerry gave Jon a Spot Award (an internal LBL award) for his efforts

- Jon then applied for a patent on the foam Dewars and started his own company 
to sell them and has done very well (personally, I find them an excellent 
alternative to the glass dewars)

Corie 

----- Original Message -----
From: Thomas Earnest <[EMAIL PROTECTED]>
Date: Thursday, October 9, 2008 4:08 am
Subject: Re: [ccp4bb] foam dewar usage ?
To: CCP4BB@JISCMAIL.AC.UK

> Jean-Baptiste,
> 
> Since these were conceived and developed by Jon Spear when he was a 
> member of my
> group (at the ALS at the time), I know a bit about these Dewars, 
> their 
> intended usage, and relative benefits.
> When Jon first made them, the beamline users and staff quickly 
> realized 
> the advantages, they spread around
> the ALS, and then to other sources. My guess is that for other 
> beamlines 
> that have both these and
> vacuum-jacketed Dewars, the users prefer these over other options.
> 
> As with all things, the advantages and disadvantages must be viewed 
> in 
> context of what the use is. The
> fact that these will not shatter, can be shaped to whatever the 
> needed 
> dimensions are and pockets can be
> machined in to allow for  transport pucks, cryo-tools, etc., they 
> cool 
> and warm rapidly and are inexpensive, are all distinct advantages. 
> Thus 
> for freezing and manipulating crystals at home or the beamline, 
> they are 
> excellent and
> inexpensive options.
> 
> Regarding the two comments that followed your post from Uwe and James:
> 
> Uwe: When using Berkeley-style pucks or Unipucks (which replicated 
> the 
> Berkeley form factor), these
> are sufficiently dimensioned, and I believe there is a version that 
> accommodates the SSRL cassette. If
> you want another dimension, I suggest contacting Jon directly and 
> discuss this with him.
> 
> James: I'm not sure why you think that chemical resistance or 
> autoclaving are relevant to the discussion, as these
> are for holding and transporting liquid nitrogen and sample 
> cryo-transport units. Also they are machined
> with a bit more precision than a "carpet knife" would give, and 
> this 
> eliminates the burrs or other bits that
> may tend to flake off, as well as allowing for shaping to need.
> 
> 
> - Thomas
> 
> 
> Thomas Earnest, Ph.D.
> Senior Scientist and Group Leader
> Structural Proteomics Development Group
> Physical Biosciences Division
> MS64R0121
> Lawrence Berkeley National Laboratory
> Berkeley CA 94720
> 
> [EMAIL PROTECTED]
> 510 486 4603
> 
> 
> 
> Jean-Baptiste REISER wrote:
> > Dear all,
> >
> > Does anyone in the biocrystallogaphy community use foam dewars 
> for 
> > handly liquid nitrogen and freezing/manipulating frozen protein 
> crystals ?
> >
> > We are interested in the following dewar package from Hampton 
> Research 
> > : 
> > 
> http://www.hamptonresearch.com/products/ProductDetails.aspx?cid=24&sid=187&pid=559>
> > But before purchasing, we would like to have any comments on the 
> > advantages and drawbacks from people who already tried those dewars.
> >
> > Thanks in advance for your help and advices.
> >
> > -- 
> >
> > *Dr JEAN-BAPTISTE REISER - Chargé de recherche CNRS*
> >
> > 
> ******************************************************************************************>
> > *Laboratoire de Cristallographie et Cristallogenèse des Protéines 
> (LCCP)*>
> > *et Partnership for Structural Biology (PSB)*
> >
> > *Institut de Biologie Structural Jean-Pierre Ebel (IBS) - CNRS - 
> CEA - 
> > UJF*
> >
> > 41, rue Jules Horowitz
> >
> > 38027 Grenoble - France
> >
> > Phone : +33 (0)4 76 20 94 49
> >
> > Fax : +33 (0)4 76 20 94 80
> >
> > E-mail : [EMAIL PROTECTED]
> >
> > Web sites : http://www.ibs.fr ; http://psb.esrf.fr
> >
> > 
> ******************************************************************************************>
>

Reply via email to