The Institute of Cancer Research


Section of Structural Biology / Section of Cancer Therapeutics



Post-doctoral Training Fellow Structural elucidation of phosphatase cancer target


(Chelsea, London & Sutton, Surrey)



The Institute of Cancer Research is one of the world's leading cancer research organisations and is internationally renowned for the quality of its science. Our mission is the relief of human suffering by pursuing excellence in the fight against cancer.



An Institute of Cancer Research-funded Postdoctoral position is available immediately in Dr. Rob van Montfort’s Structure-Based Drug Design group. The successful candidate will work on the structure elucidation of a phosphatase implicated in cancer and be involved in subsequent structural studies to investigate the protein-ligand interactions of small molecule inhibitors bound to the protein. The post-doc will be expected to interact closely with biologists, computational chemists and medicinal chemists throughout The Institute and will work across two sites in Chelsea, London and Sutton, Surrey.



The Structure-Based Drug Design group is a joint initiative between the Section of Structural Biology and the Section of Cancer Therapeutics at the ICR. The Institute is exceptionally well equipped for all aspects of drug discovery, with state-of-the-art laboratories for molecular biology, recombinant expression in bacterial and eukaryotic systems, biochemistry, X-ray crystallography and medicinal chemistry.



Applicants must have a PhD in a biological or physical science, and experience in macromolecular crystallography / crystallisation (to include protein biochemistry, protein crystallisation, & protein crystallography). Experience in molecular biology, protein purification, and/or Structure-Based Drug design will be an advantage.



The starting salary for the position will be in the range £29,256 to £31,551 p.a. inclusive (based on previous post-doctoral experience) and the post is offered initially on a fixed term contract of up to 18 months. Informal enquiries to [EMAIL PROTECTED] Please DO NOT send your application to Dr. van Montfort; CVs must be submitted in line with the instructions below.



For further particulars and details of how to apply, please visit our website at www.icr.ac.uk. Alternatively you may call our 24 hour recruitment line on 020 7153 5475 quoting reference number C183.



Closing date:                          Friday 31 October 2008

Interviews to be held:            Week commencing 17 November 2008


Dr. Rob van Montfort
Team Leader Structure-Based Drug Design
Sections of Cancer Therapeutics and Structural Biology
The Institute of Cancer Research
15 Cotswold Road
Sutton SM2 5NG
UK

Tel:
+44-(0)20-8722-4364 (Sutton)
+44-(0)20-7153-5142 (Chelsea)
Email: [EMAIL PROTECTED]


The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company 
Limited by Guarantee, Registered in England under Company No. 534147 with its 
Registered Office at 123 Old Brompton Road, London SW7 3RP.

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