Hi experts, whenever create a ligand description with the sketcher that contains a saturated ring with nitrogens (piperidine, piperazine, etc) it flattens the nitrogens a la sp2 and consequently does weird things to the ring puckering. One can artificially protonate the nitrogen to get a sp3 geometry or fiddle around with the cif file. Is there a proper way to make it right in the first place?
Thanks Jan
