Dear All,
Here are updated details for the high R problem of my 1.75A structure. 1. Protein 100 aa, peptide 6 aa, co-crystalized 2. Space group: P43212. Overall R-fac: 0.3. Redundancy: >5 for 98% of reflections. B-factor:55 3. CNS refinement 4. Phenix xtriage checked, no twinning is suspected. 5. Water molecules added Thanks a lot for all your comments and suggestions. Best, Jinjin Zhang
