Structural Chemistry, Structure-Based Drug Design & Discovery Novartis Institutes for BioMedical Research, Emeryville, California
Use your scientific expertise to aid us in our structure-based drug design efforts. Your task will be the determination of high-resolution, three-dimensional structures of macromolecular drug targets (typically proteins), including crystallization and structure solution of medically important structures and target-ligand complexes. As a part of an integrated team you will interact with computational chemists and medicinal chemists to design new scaffolds and improve lead compounds. The ideal candidate will have an M.S. degree and 7 or more years of work experience or a Ph.D. and 3-6 years of postdoctoral and/or work experience. Degrees in Biochemistry, Chemistry, or Molecular Biophysics are acceptable. Strong experience in protein biochemistry and crystallographic methods is necessary and pharmaceutical industry experience is a plus. Strong computational and molecular modeling skills, experience in solution studies (calorimetry, NMR, etc.), experience in structure-based drug design, and/or expertise in complex crystallization problems would be useful. You should have excellent verbal and written communication skills and the ability to work in large, multidisciplinary project teams. To join our global team, please submit your CV online at http://www.novartisvaccines.com/jobs <http://www.novartisvaccines.com/jobs> , referencing Brassring requisition number 2294. Any questions about the position should be sent to [EMAIL PROTECTED] <mailto:[EMAIL PROTECTED]> . Dirksen Bussiere, Ph.D., M.B.A. Computational Chemistry & Structural Chemistry Novartis Institutes for Biomedical Research 4560 Horton Street, M/S 4.4 Emeryville, CA. 94608 Phone: 510-923-2114 Fax: 510-923-5550 e-mail: [EMAIL PROTECTED]