Structural Chemistry, Structure-Based Drug Design & Discovery

Novartis Institutes for BioMedical Research, Emeryville, California

     

     Use your scientific expertise to aid us in our structure-based drug
design efforts. Your task will be the determination of high-resolution,
three-dimensional structures of macromolecular drug targets (typically
proteins), including crystallization and structure solution of medically
important structures and target-ligand complexes.  As a part of an
integrated team you will interact with computational chemists and
medicinal chemists to design new scaffolds and improve lead compounds.
The ideal candidate will have an M.S. degree and 7 or more years of work
experience or a Ph.D. and 3-6 years of postdoctoral and/or work
experience.   Degrees in Biochemistry, Chemistry, or Molecular
Biophysics are acceptable. Strong experience in protein biochemistry and
crystallographic methods is necessary and pharmaceutical industry
experience is a plus.  Strong computational and molecular modeling
skills, experience in solution studies (calorimetry, NMR, etc.),
experience in structure-based drug design, and/or expertise in complex
crystallization problems would be useful.  You should have excellent
verbal and written communication skills and the ability to work in
large, multidisciplinary project teams. 

 

To join our global team, please submit your CV online at
http://www.novartisvaccines.com/jobs
<http://www.novartisvaccines.com/jobs>  , referencing Brassring
requisition number 2294.

 

Any questions about the position should be sent to
[EMAIL PROTECTED] <mailto:[EMAIL PROTECTED]> .

 

Dirksen Bussiere, Ph.D., M.B.A.

Computational Chemistry & Structural Chemistry

Novartis Institutes for Biomedical Research 

4560 Horton Street, M/S 4.4

Emeryville, CA.  94608

Phone: 510-923-2114

Fax:  510-923-5550

e-mail:  [EMAIL PROTECTED]

 

 

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