Postdoctoral Research Position
MECHANISMS OF DNA DOUBLE-STRAND BREAK REPAIR
Applicants are invited to apply for a postdoctoral fellowship in the area
of double-strand break repair in prokaryotic cells. Most bacteria, in
common with eukaryotes, maintain a conserved non homologous end-joining
(NHEJ) repair pathway required to repair DNA double strand breaks. The aim
of this project is to study the function of this NHEJ complex in DNA break
repair processes in bacteria. In particular, we would like to address the
biochemical and cellular mechanisms of this repair system.
Applicants must have extensive experience in using biochemical/structural
and molecular biology techniques to study DNA metabolic enzymes. Experience
in studying biochemical and structural aspects of DNA repair proteins would
be particularly desirable but other applicants with relevant experience
will also be considered.
The Genome Damage and Stability Centre is an internationally renowned
Institute carrying out research on the response of cells to DNA damage,
genome instability and its relationship to human disease. We provide a
stimulating and supportive environment and our expertise covers a range of
experimental systems. Further information about our research can be
obtained from our website at http://www.sussex.ac.uk/gdsc/
See relevant references:
Weller et al. (2002) Science 297,1686-1689.
Della et al. (2004) Science 306, 683-685.
Pitcher et al. (2007) Ann. Rev. Microbiol. 61, 258-282.
Pitcher et al. (2007) DNA Repair 6, 1271-1276.
Brissett et al. (2007) Science 318, 456-459.
The post is initially for 18 months with the prospect of extension for a
further period.
The position is available from May 1st, 2008.
Applications
Informal enquiries to: Dr Aidan Doherty (E-mail:[EMAIL PROTECTED]; Tel:
01273 877500). Applications, including a CV with contact details of two
referees, should be sent to: [EMAIL PROTECTED]
Closing date for applications: 14th of April, 2008.
The University of Sussex is committed to equality of opportunity
