It is difficult at the end of refinement - the small corrections hardly
affect the R values, but should make the maps look cleaner.
And R values are very correlated with the tightness of your geometric
restraints - maybe you are changing these slightly too?
I presume you are describing small shifts - if R values increase by 1%
there probably is something wrong.
Eleanor
U Sam wrote:
Hi Everybody,
I have small query.
I am feeding ions and correcting few residues into my final structure.
If R increases and Rfree decreases or vice versa in the subsequent refinement,
which one I should accept and go forward.
Thanks.
Sam
_________________________________________________________________
Discover the new Windows Vista
http://search.msn.com/results.aspx?q=windows+vista&mkt=en-US&form=QBRE
