Hi, All, I am trying to refine a model with ligand. The problem is:The electron density of ligands can be seen on the map prepared by resolve . After rebuilding the ligand into the model by coot and refienment using refmac, the electron density of the ligands was very poor on the map prepared by refmac. What shall I do after this? refine using resolve or others?
Thank you very much in advanced! Best wishes! leo
