Looking into NetworkManager documentation, it looks like the 'networking service provided by Guix does not implement the NetworkManager's systemd equivalent. [1]
Namely, NetworkManager has some specific steps until it can be considered up and running/"startup complete". [1] This process seems mostly dependent on nm-online to query the actual NetworkManager state. [2] [1]: https://networkmanager.dev/docs/api/latest/NetworkManager-wait-online.service.html [2]: https://networkmanager.dev/docs/api/latest/nm-online.html