I tried building again using: guix build --cores=1 /gnu/store/mw6ax0gk33gh082anrdrxp2flrbskxv6-openssl-1.1.1n.drv
This made it more clear that the error was an expired certificate: ../test/recipes/80-test_ssl_new.t .................. Dubious, test returned 1 (wstat 256, 0x100) Failed 1/29 subtests I was able to work around that by adjusting the machine time: sudo timedatectl set-ntp no sudo date --set "28 may 2022 15:00:00" guix build .... sudo timedatectl set-ntp yes