The execution of Snakemake workflows fails on a cluster because the script that Snakemake executes remotely does not reference Python correctly.
This is due to a patch applied in the Guix package definition (build phase call-wrapper-not-wrapped-snakemake, https://git.savannah.gnu.org/cgit/guix.git/tree/gnu/packages/python-xyz.scm#n9713) which is outdated. The corresponding code in Snakemake was changed significantly in the following commit: https://github.com/snakemake/snakemake/commit/e87cc979bea0567e1cd97722d385f472857df83c#diff-438f3317205fd7130727d0589d2fc1a6c2e1f6fc48c2c04d354a8a09b91ba2f4 Cheers, Konrad