I have succesfully installed guix in trisquel 9 (mate). I have installed some packages and everything is working as expected.
$ guix package --list-installed dino 0.2.1 out /gnu/store/nlprjzilka7i79fwwjbxxagwjzx5 6z4s-dino-0.2.1 fontconfig 2.13.1 out /gnu/store/k6zs6zabhfybh6aphc4988wc2fsy k5hh-fontconfig-2.13.1 font-liberation 2.1.4 out /gnu/store/qw087yajzsq8mjvq3nkxr3grmp3k zcja-font-liberation-2.1.4 font-dejavu 2.37 out /gnu/store/7y3lvk3xf4im8n44337mc6y0ccys vfia-font-dejavu-2.37 glibc-locales 2.31 out /gnu/store/wnw0nwlyg92vv33f5f65jj1rd3p4 fi3c-glibc-locales-2.31 But when I install gnucash, or cawbird and reboot the system doesn't autologin and stays at login screen. Inserting the password is just getting me back to the login screen. To log in back again I do guix package --roll-back and then reboot. The only error I have after that is that my panel notification applet crashes (reloading works fine).