Since commit 065a5ed677cdd1a65acae20f185d7c4bd23b1f2c wine and wine64 are upgraded to version 5.12. The latter segfaults when doing anything other than wine --help or wine --version. (Try for example wine regedit or winecfg).
The old 5.3 version continues to work after roll-back, and would probably also work through inferiors. I am currently checking previous versions of wine64-staging with guix time-machine to see at which point the error might have been introduced. Until now, version 5.6 from 7b23a69d6b97c463cb1ef237931af11c22c19c67 fails with the following output: 000b:fixme:winediag:__wine_start_process Wine Staging 5.6 is a testing version containing experimental patches. 000b:fixme:winediag:__wine_start_process Please mention your exact version when filing bug reports on winehq.org. 0009:err:module:LdrInitializeThunk "kernelbase.dll" failed to initialize, aborting 0009:err:module:LdrInitializeThunk Initializing dlls for L"C:\\windows\\system32\\winecfg.exe" failed, status c0000005 Regards, Leo