Hi, I do experiment the same issue.
--8<---------------cut here---------------end--------------->8--- $ guix describe Generation 56 Nov 19 2019 12:52:57 (current) guix 7b40d59 repository URL: https://git.savannah.gnu.org/git/guix.git branch: master commit: 7b40d59114e1462d6d8140f325a66b12e91db667 --8<---------------cut here---------------end--------------->8--- --8<---------------cut here---------------end--------------->8--- $ ls -l `which emacs` lrwxrwxrwx 2 root root 64 Jan 1 1970 /home/simon/.guix-profile/bin/emacs -> /gnu/store/vb0ia0qnkc92yp771hxhcp8k6ywqymkk-emacs-26.3/bin/emacs --8<---------------cut here---------------end--------------->8--- Then "emacs -Q" works fine. However "emacs -q" does not. All the best, simon