The article at <https://distrowatch.com/weekly.php?issue=20190624#guixsd> mentions things like:
For instance, after installing Icecat, I installed a few other desktop programs and then found Icecat had disappeared from my path again. It’s likely that the person ran several ‘guix package’ commands in parallel, and that one undoed the effects of the other. Julien suggested that ‘guix package’ could grab a lock file, and I guess it could simply error out when the lock is already taken. Ludo’.