----- Original Message ----- 
From: "David Hobby" <[EMAIL PROTECTED]>
To: "Killer Bs Discussion" <[email protected]>
Sent: Friday, November 24, 2006 10:45 PM
Subject: Re: It ain't the genes that are different, it's the number of 
copies . . .


> [EMAIL PROTECTED] wrote:
> ...
>> The genome is already messy. The notion that are chromosomes have a 
>> neat  lineup of genes is incorrect. There are insertions into the 
>> middle of genes  (introns). Many genes are spread over 
>> discontinuous aspects of a single  chromosome. Some insertions into 
>> the middle of genes destroy function but many  do not.
>
> Yes, I know that.  But if everybody's genome is messy
> in the same way, then their chromosomes can still match
> up quite well.  Are there variations between people in
> terms of what/where the introns are?
>
> I wish Alberto would chime in, but it seems that you don't
> understand the question:  "Isn't it sometimes bad when an
> individual has a pair of chromosomes that don't match up
> well?"  (Which would be produced if their parents had
> different numbers of various genes, right?)
>
> As far as I can tell, the answer is that it's not that
> bad.  (Although I get the sense that we don't yet understand
> enough about the role of wrapping/unwrapping DNA to give
> a definitive answer.)  It's certainly bad if it gets to the
> point where chromosomes don't segregate properly at meiosis,
> but that's when the match ups between chromosome pairs are
> really poor.
>

What is it?.........1/3 to 1/2 of conceptions spontaneously abort?!!?
Does this connect here?
And how would it work if it does?

xponent
Too Many Chemicals Maru
rob 


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